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Benzylpenicillin quot;Panpharmaquot; skal anvendes med forsigtighed: Ved sv#230;r overf#248;lsomhed for andre antibiotika, som fx cefalosporiner og carbapenemer, pga. risiko for krydsallergi.; Ved enhver behandling med et antibiotikum kan bakterierne blive uf#248;lsomme (resistente) over for det anvendte middel og eventuelle andre er dog blandt de antibiotika, der udvikler mindst
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(Panpharma) NB! Se eget blandekort for Penicillin (Actavis) Styrke Staml#248;sning Videre fortynning Administrasjon Holdbarhet Merknader 600 mg = 1 mill IE inj. subst. Tilsett 6 ml 1, sterilt vann til 600 mg t#248;rrstoff * 100 2,31mg/ml kan gis ufortynnet2 300 mg/ml m#229; fortynnes videre2 Fortynningsv#230;ske2,3: NaCl 9 mg/ml eller glukose 50 mg/ml 3 g
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Benzylpenicillinnatrium (Gpenicillin) omregning: 0,6 g svarer til 1 mill. IE ; 1 g svarer til 1,67 mill. IE ; 1 mg svarer til IE. pH pH efter opl#248;sning 5,57,5. Tilberedning af injektionsv#230;ske Til injektion opl#248;ses 0,6 g (1 mill. IE) i 2 ml sterilt vand eller lidocainchloridinjektionsv#230;ske 10 mg/ml.
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Penicillin resistance can be mediated by alteration of penicillin binding proteins or development of betalactamases. Resistance to penicillin may be associated with crossresistance to a variety of other beta lactam antibiotics either due to a shared target site that is altered, or due to a betalactamase with a broad range of substrate molecules.
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